代謝症候群與下泌尿道症狀之關聯性

李亞哲、陳丕哲

嘉義基督教醫院 外科部 泌尿科

 Relationship between Metabolic Syndrome and Lower Urinary Tract Symptoms

Ya-Che Lee, Pi-Che Chen

Divisions of Urology, Department of Surgery, Chiayi Christian Hospital

Introduction: Metabolic syndrome (MS) has become a global public health and has been suggested to be a risk factor for Lower urinary tract symptoms (LUTS). The aim of the study was to test the hypothesis that the MS is linked to LUTS.

Methods and Material: In this study, 54 patients referred to urology policlinic with LUTS were retrospectively scanned between September 2019 and March 2020. Patients were assessed using the International Prostate Symptom Score (IPSS) and all the data of the patients' body, including Body Mass Index (BMI), lipid parameters, preprandial blood glucose, and waist circumference. The MS was defined according to the International Diabetes Federation consensus definition of 2005, and LUTS were quantified using IPSS.

Results: Of all patients, the mean age was 68.8 years. The prevalence of the MS was 6/54 (11.1%) in our study, respectively. There were 21 patients (39%) with mild IPSS (0~7); 31 patients (57%) with moderate IPSS (8~19) and 3 patients (4%) with severe IPSS (20~35). There was no significantly greater increase in the IPSS in men with the MS than in men without the MS (14.5 ± 7.90 versus 9.58± 5.07, p=0.068). In the comparison of the two groups in the point of IPSS parameters, significant correlation was detected in the ‘Nocturia’(P<0.05), with the average 3.33 points in the patients with MS group and 1.78 points in the patients without MS group. Metabolic syndrome was negatively correlated with other voiding and storage scores.

Conclusions: In our study, the evidence is not enough to support the hypothesis of the relevance between MS and LUTS. But, this study may support the hypothesis that the MS is linked to nocturia. Wide-ranging and prospective studies are needed to research the relevance between MS and LUTS