D型人格可預測女性非神經性排尿障礙患者之較差生活品質

林巧文¹ 范玉華^1,2 顧明軒^1,2 林志杰^1,2 林登龍^1,2 黃志賢^12,

¹台北榮民總醫院泌尿部

²國立陽明交通大學醫學院泌尿學科及書田泌尿科學研究中心

Type D Personality is a Predictor of Worse Quality of Life in Women with Non-Neurogenic Voiding Dysfunction

Chyau-Wen Lin¹, Yu-Hua Fan^1,2, Ming-Hsuan Ku^1,2, Chih-Chieh Lin^1,2, Alex T.L. Lin¹, William J.S. Huang^1,2

¹Department of Urology, Taipei Veterans General Hospital, Taiwan

²Department of Urology, College of Medicine and Shu-Tien Urological Institute, National Yang Ming Chiao Tung University, Taipei, Taiwan

Purpose

Type D personality (TDP) describes a tendency towards negative affectivity and social inhibition, and is associated with worse outcomes in cardiovascular disease. However, the relationship between TDP and lower urinary tract dysfunction/symptoms (LUTS) is not explored. We investigated the relationship between TDP, LUTS and urodynamic characteristics in patients with voiding dysfunction

Material and Methods

This was a prospective single-center cross-sectional study conducted between December 2020 and January 2022. Female patients with voiding symptoms who underwent video-urodynamic study were recruited. Patients with overt neurological disorders or a history of lower urinary tract surgery were excluded. TDP was assessed using the Type D Scale-14 (DS14). LUTS were assessed using the International Prostate Symptom Score (IPSS), Overactive Bladder Symptom Score (OABSS) and Urogenital Distress Inventory-6 (UDI-6).

Results

Fifty patients were enrolled, and the mean±SD age was 60±13.9 years. Of these, 18 (36%) met the criteria for TDP. The patients with TDP were significantly younger (55.5-year-old) compared with those without TDP (55.5 years vs. 62.7 years, p=0.012). The IPSS Q2 (frequency) was significantly higher in patients with TDP (4.3 vs. 3.1, p=0.022). IPSS quality of life score in patients with TDP was significantly higher than those without TDP (5.1 vs. 4.0, p<0.001). There was no significant difference in other total and subscores of questionnaires for LUTS. Furthermore, the prevalence of fluoroscopic bladder outlet obstruction, detrusor-sphincter dyssynergia, reduced rate of uroflow and post-void residual were similar between patients with TDP and those without TDP.

Conclusion

We observed that 36% of women with non-neurogenic voiding dysfunction had TDP. TDP was associated with increased severity of urinary frequency and worse quality of life.