固態耦合物質應用於體外震波碎石術之效力的觀察性研究
吳冠賢1、林崇裕1、阮雍順1,3,4、吳文正1,3,4、陳偉權1,2*
1高雄醫學大學附設醫院泌尿部，2臨床教育訓練部；3高雄醫學大學 醫學院醫學系泌尿科，4醫學院臨床醫學研究所
Experimental Observation of Isolative Efficacy of Solid Coupling Medium in Extracorporeal Shock Wave Lithotripsy
Kuan-Hsien Wu1, Chung-Yu Lin1, Yung-Shun Juan1,3,4, Wen-Jeng Wu1,3,4, Wei-Chuan Chen1,2*
1Department of Urology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
2Department of Clinical Education and Training, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
3Department of Urology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
4Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
Introduction: Extracorporeal shock wave lithotripsy (ESWL) is a standard treatment method in the clinical treatment of urinary calculi. When the probe of lithotripter is in direct contact with the human body, a semi-liquid gel is usually used as the coupling material between the skin and the probe. If the gel on the probe has contact with the wound on the skin, it might contaminate the probe and spread body fluid and blood between the patients undergoing ESWL. This study aimed to investigate the isolative efficacy of icPad in blocking the permeation of fine particles such as bacteria and viruses.
Materials and Methods: The experiment was divided into three groups: experimental group, control group and blank group. The experimental group received ESWL, and the frequency and output energy of shock wave was set according to clinical guideline. The fluorescent dye was used as simulating pollutants such as blood and viruses. Qualitative and quantitative analysis were applied for analyzing the degree of the fluorescent dye distributed on the probe surface. In the qualitative analysis part of the control group, icPad was cut into slices, and placed the section under a microscope to measure the longitudinal permeation. In the quantitative analysis part, we measured the fluorescence intensity of icPad with a fluorescence spectrometer. The experiments of each group were repeated three times.
Results: Qualitative and quantitative analysis results confirmed that icPad has an isolation effect on pollutants.
Conclusions: This experimental and observational study is the first time to investigate the isolation efficacy of icPad during ESWL. Comparing to semi-liquid gel, using icPad as the coupling medium can effectively isolate the direct contact between the probe and the patient’s skin and to block the permeation of fine pollutants.