核磁共振用於前列腺癌之診斷：彰基經驗
簡佑全、王百孚
彰化基督教醫院 外科部 泌尿科
Accuracy of Magnetic Resonance Imaging for Prostate Cancer: experience in changhua christian hospital
You-Chiuan Chien, Bai-Fu Wang
Divisions of Urology, Department of Surgery, Changhua Christian Hospital, Changhua, Taiwan;
Purpose: To evaluate the accuracy of MRI acquisition for staging of prostate cancer (PCa) in robot-assisted laparoscopic radical prostatectomy (RALAP).
Materials and Methods: 33 consecutive patients underwent a multiparametric MRI protocol prior to RALAP. Analyses were carried out to predict side-specific extracapsular extension (ECE) using variables determined preoperatively, including 3.0-Tesla magnetic resonance imaging findings (T2-weighted and diffusion-weighted imaging). A prediction model was then constructed and applied to the validation study sample.
Results: Of 33 eligible patients, histology showed ECE in 14 (42%) cases. MRI sensitivity and specificity to detect ECE were 40 and 86%.
Conclusions: MRI provides a high specificity and relatively low sensitivity for local staging of prostate cancer.