2高雄榮民總醫院 外科部 泌尿外科
Synchronous ipsilateral renal cell carcinoma and urothelial carcinoma of kidney or ureter : cases report and literature review
Yu-Cheng Chang12, Chia-Cheng Yu and Tony T. Wu
1Division of Urology, Kaohsiung Municipal Min-Sheng Hospital,
2Division of Urology, Department of Surgery, Kaohsiung Veterans General Hospital
We report 2 cases ( a 63-year-old female and a 60-year-old female ) were diagnosed of i Simultaneously ipsilateral urothelial carcinoma (UC) of upper urinary tract and renal
Cell carcinoma (RCC) had the symptoms of painless gross hematuria and confirmed by pathological document .
Materials and Methods:
In case 1 : The abdominal computed tomography (CT) scan was described as left upper third ureter tumor with extension to renal pelvis, measured about 4 cm in size, with post-contrast enhancement, urothelial cancer was considered. In case 2 : The abdominal computed tomography (CT) scan found a suspicious focal enhanced area is noted in right kidney, 1.5 cm, RCC cannot be excluded, the findings should be differentiated with infiltrated TCC in calyx.
In case 1 : She received the operation of anterior exenteration and the pathology showed urothelial carcinoma of left U/3 Ureter and clear cell type renal cell carcinoma. In case 2 : She received right nephroureterectomy with bladder cuff excision for urothelial carcinoma of renal pelvis and unclassified renal cell carcinoma.
The most symptoms of the synchronous RCC and UC are flank pain and gross hematuria. Synchronous RCC and UC of the same kidney is a rare condition and surgical intervention of radical nephroureterectomy with bladder cuff excision may be a curative treatment for clinically localized tumor.