國泰綜合醫院 外科部 泌尿科
Vescoureteral Reflex (VUR) treated with subureteric deflux injection of Deflux：5 years experience in Cathay General Hospital
Shu-Wei Tsai Wah-On Lo
Division of Urology, Department of Surgery, Cathay General Hospital
Vescoureteral Reflex (VUR) is one of the most common congenital urological disease and can lead to hydronephrosis and renal function impairment. VUR in children has been treated with subureteric deflux injection of Deflux (dextranomer hyaluronic acid copolymer) since 2009. The aim of this study was to analyze the results of endoscopic treatment of VUR in our hospital during the last 5 years.
Materials and Methods:
We reviewed the medical records of patients with VUR in our hospital. The perioperative data and post-operative results were collect in this study.
Between July 2009 and Sep 2014, 12 patient (10 children and 2 adults) underwent endoscopic subureteral injection of Deflux in 13 ureters. Three months postoperatively voiding cystourethrogram (VCUG) was performed.
The study included 12 patients (5 females and 7 males) with 13 refluxing ureters. All patients were treated, from the age 1years old up to 43 years old. The mean age of patients was 10.7 years old (mean age of children was 5.8 years old). There has been no complications, but with few recurrences. In 1 patients (16.6%), endoscopic treatment with deflux was done twice, while in 1 patients (8.5%), the endoscopic treatment with deflux was performed three times, because of recurrence.
We recommend the use of endoscopic Deflux injection as first line treatment for children with VUR .Endoscopic subureteral injection of Deflux is a minimally invasive method for VUR treatment in pediatric patients and is associated with low morbidity.