彰化基督教醫院 外科部 泌尿科
Comparison of surgical intervention and non-surgery result in early prostate cancer
Ping-Hao Tsai, Sheng-Hsien Huang, Bai-Fu Wang
Divisions of Urology, Department of Surgery, Changhua Christian Hospital, Changhua, Taiwan
Long term benefit of radical prostatectomy in early prostate cancer is publish in 2014. We would like to investigate our data according to this result. We will compare surgical intervention with non-sugical intervention.
Materials and Methods:
We use retrospective study to review our data in the past ten year from 2004-2014. According to N Engl J Med 2014;370:932-42, there was long term benefit in early prostate cancer who received radical prostatectomy. This study comparison surgey with watchful waiting. To-date, active surveillance is a better way for follow up. We include patient who under active surveillance to compare to surgery group.
We will set primary endpoint as mortality in 5 year due to prostate cancer and secondary endpoint as how many will receive androgen-deprivation therapy after radical prostatectomy.
To investigate our result of radical prostatectomy comparison to active surveillance in early prostate cancer. We will like to see a benefit result in 5 year cancer-free survival, PSA regression in surgery group. In addition, we also like to know the possibility of androgen-deprivation therapy after radical rostatectomy.