Evaluation the Relationship and post-operative GFR between the Living Donor and the Recipients in Kidney Transplantation
Guang-Heng Chen, His-Hsien Wang , Po-Jen Hsiao , Yi-Huei Chang , Shen-Wei Li , Chi-Ping Huang Hsi-Chin Wu, Chao-Hsiang Chang
Department of Urology, China Medical University Hospital, Taichung, Taiwan
Purpose: This study evaluate the relationship and post-operative GFR between the living donor and the recipients in kidney transplantation . A 5-year review of living donor renal transplants in a single transplant center was performed.
Materials and Methods: Between January 2010 until February 2015, a total of 49 living donor KTs were performed at China Medical University Hospital. Relationship between donor and recipient and graft survival and changes in GFR during a 5-year period in a single center were retrospectively analyzed.
Results: These 49 living donor kidneys transplants represent 52% of all transplants performed during this 5-year review. The recipients’ kidney involved from sibling donation (22.4%, mean age 37.18), parents donation (32.7%, mean age 27.56), offspring donation (22.4%, mean age 54.27) and spouse donation (22.4%, mean age 49.09). The GFR of the recipients had significant difference between these four groups during the following periods . The mean last follow-up postoperative GRF of the recipients was 77.71ml/min for offspring donors , 57.81ml/min for parents donors, 65.91ml/min for sibling donors and 42.91ml/min for the spouse donors respectively (p=0.04). The numbers of female donors were more than the male donors(32 vs 17). Two grafts loss were noted all in the spouse living donor population due to infection (CMV virus and urinary tract infection).
Conclusions: This review of center-specific data shows that the relationship of the donor to their recipient has make a significant difference on the post-operative GFR and graft loss of the recipients. The recipients’ kidney donated from the spouse the had worst GFR compared to the others groups.