Non-muscle invasive bladder cancer with prostatic stroma invasion: A case report and review of literature
Chu-Wen Fang, Mon-I Yen, Bai-Fu Wang, Jian-Ting Chen, You-Chiuan Chien
Division of Urology, Department of Surgery, Changhua Christian Hospital, Taiwan
The face of bladder cancer is heterogeneous, with about 70% presented with superficial tumors, which tend to recur but are generally not life threatening, and 30% presented as muscle-invasive disease that associated with high mortality rate due to distant metastases .
There were little information about infiltrating urothelial carcinoma metastatic to prostate without bladder wall invasion. Herein, we report a case of non-muscle invasive bladder cancer (NMIBC) with prostate invasion.
A 73 y/o male with aggravated left flank pain was admitted to our institution for study, the abdominal CT revealed suspicious neogrowth in the urinary bladder. He refused to receive cystoscopy examination and then discharged. However, he returned 18 months later with persistent gross painless hematuria and urinary retention for one month. The IVP showed indentation of the bladder base and prostatic enlargement. Then he received TURP and TUR-BT. The tissue pathology reported that there were infiltrating urothelial carcinoma in urinary bladder with no muscle invasion and infiltrating urothelial carcinoma in prostatic stroma by invasion (pT4N0M0). However, there were negative for malignancy in urinary bladder base and margin. After surgery, he received radiotherapy and chemotherapy.