1奇美醫學中心外科部泌尿外科; 2高雄榮民總醫院外科部泌尿外科, 3病理檢驗部
Occurrence of paratesticular ganglioneuroma 18 years after concurrent adrenal ganglioneuroma and papillary thyroid carcinoma– a case report and literature review
Chu-Wen Fang1, Jen-Tai Lin2, Tony T. Wu2, Jyh-Seng Wang3
1Division of Urology, Department of Surgery, Chi Mei Medical Center, Tainan, Taiwan
2Division of Urology, Department of Surgery, and 3Department of Pathology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
The ganglioneuroma (GN) is composed of mature ganglion cells and Schwann cells with fibrous stroma, which is most often seen in children and young adults. The majority of non-cranial GNs are located in retroperitoneum and posterior mediastinum. Other reported rare sites include adrenal gland, small intestine, colon and urinary bladder. Yet, para-testicular GN is even rarer. Herein, we report the first case of concurrent adrenal GN and thyroid papillary carcinoma that developed paratesticular GN eighteen years later.
After review of literatures, we found evidences showed that there might be association between papillary thyroid carcinoma, GN and multiple endocrine neoplasm type 2 syndrome. Thus, our case may provide an important information for this association. However, further studies were required.