NDP011: Mediastinal mixed germ cell tumor in an infertile male with klinefelter syndrome:a case report and literature review.
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  • 2017-12-25,
  • 上傳者: TUA秘書處,
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柯林菲特氏症患者併縱膈腔生殖細胞瘤-案例報告及文獻回顧
金介文 蔡政諭 余家政
高雄榮民總醫院外科部泌尿外科
Mediastinal mixed germ cell tumor in an infertile male with Klinefelter syndrome:A case report and literature review.
Chieh-Wen Chin, Jeng-Yu Tsai, Chia-Cheng Yu
Divsion of Urology, Depart of Surgery, Kaohsiung Veterans General Hospital
 
Klinefelter syndrome (KS) is a well-documented abnormality of the sex chromosome, with an incidence of 1 in 600 newborn males. It is characterized by a 47, XXY or a mosaic karyotype, hypergonadotrophic hypogonadism, infertility, reduced body hair, gynecomastia, and tall stature. Different neoplasms such as breast, testicular, and lymphoreticular malignancies may occur in 1% to 2% of the cases with KS. Here we describe a case of mediastinal mixed germ cell tumor (GCT) in a 17-year-old male with KS. Mediastinal mixed germ cell tumor was removed smoothly. York cell tumor component was 20% in the tumor and matured teratoma was 80%. After operation and chemotherapy, AFP level was reduced to normal. Klinefelter syndrome diagnosis was made due to azoospermia. The patient will follow up after chemotherapy.
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    發表時間 :
    2017-12-25 17:03:19
    觀看數 :
    288
    發表人 :
    TUA秘書處
    部門 :
    台灣泌尿科醫學會
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