Association of prostate blood flow with male lower urinary tract symptoms
Kuan-Yu Wu, Yuh-Shyan Tsai, I-Hung Chen, Yung-Ming Lin, Tzong-Shin Tzai, Yat-Ching Tong
Department of Urology, College of Medicine and Hospital, National Cheng Kung University, Tainan, Taiwan
Purpose: To investigate the association of prostate blood flow with lower urinary tract symptoms in aged male using Doppler spectral waveform (DSW) analysis.
Materials and Methods: We performed a prospective analysis involving 133 aged male patients with clinically imaged benign prostatic hyperplasia. DSW parameters [peak-systolic velocity (PSV), end-diastolic velocity (EDV), and resistive index (RI)] were measured at bilateral neurovascular bundle (NVB) vessels and their urethral and capsular branches via Doppler transrectal ultrasound at the right lateral decubitus position. The association of these parameters with lower urinary tract symptoms scred with international prostate symptom score (IPSS) were analyzed.
Result: Overall, total IPSS scores were significantly associated with RI of each NVB vessels (r2 = 0.03, 0.04; p = 0.04, 0.02, respectively), as well as PSV of left PSV vessels. PSV of both NVB vessels is associated with the storage score (p = 0.022 and 0.016), rather than with the voiding score. The summation of frequency and urgency score is also associated with EDV of bother capsular and urethral branches (p = 0.043 and 0.009, respectively), as well as PSV of NVB vessels at both sides (p = 0.045 and 0.019, respectively).
: The association of prostate blood flow and lower urinary tract symptoms exists, mainly with storage symptoms. This finding may provide some information in searching the underlying the etiology.