(MP2-5) Urolithiasis is associated with higher prevalence of low serum testosterone level in patients with erectile dysfunction
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  • 2015-11-30,
  • 上傳者: TUA秘書處,
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有尿路結石的勃起功能障礙病患較常出現血液中睪固酮的濃度低下
歐穎謙、黃鶴翔、林永明
國立成功大學醫學院附設醫院 泌尿部
Urolithiasis is associated with higher prevalence of low serum testosterone level in patients with erectile dysfunction
Yin-Chien Ou, Ho-Shiang Huang, Yung-Ming Lin
Department of Urology, National Cheng Kung University Hospital, Tainan, Taiwan
 
Purpose:
Both stone disease and erectile dysfunction (ED) are currently considered as systemic diseases which may associate with several systemic risk factors, such as hypertension (HTN), diabetes mellitus (DM), dyslipidemia, smoking, obesity, and hypogonadism. The aim of this study is to evaluate the prevalence of urolithiasis in patients with ED, and to show which risk factors may relate to stone formation.
Materials and Methods:
From May 2014 to September 2015, total 186 patients presented to our out-patient clinic with chief complaint of ED were prospectively enrolled. The clinical characteristics, underlying diseases, current medications, IIEF-5 questionnaire, biochemical profiles and self-report history of urolithiasis were collected. We further divided these patients into stone positive group and stone negative group. The Fisher’s exact test were used to evaluate the different prevalence of risk factors between these two groups.
Results:
Of the 186 patients, 21 (11.3%) reported history of urolithiasis, and were divided in the stone positive group. The other 165 patients were in the stone negative group. This prevalence rate in the ED population is higher but not statistically different from previous study of the general population of southern Taiwan. The average age, IIEF score, prevalence of HTN, DM, dyslipidemia, smoking and obesity were compatible between the two groups without difference. By contrast, 8 (38.1%) patients in the stone positive group have low serum testosterone level, which is significant higher compared to 20 (12.1%) from the stone negative group (P=0.005).
Conclusions:
In patients with ED, we found a higher incidence of stone prevalence. For ED patients with urolithiasis, higher prevalence of low serum testosterone level was found compared to those without urolithiasis.
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    2015-11-30 13:19:00
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