奇美醫學中心 外科部 泌尿外科 ，1泌尿腫瘤科
Renal Classic and Epithelioid Angiomyolipoma- Experience of Chi Mei Hospital and Literatures review
Ming-Hsiang Kuo, Steven Kuan-Hua Huan1
Division of Urology, Department of Surgery, 1Division of Uro-Oncology
Chi-Mei Medical Center, Tainan, Taiwan
Renal angiomyolipoma (AML) is a benign neoplasm. There are two major histologic types of AMLs: classic and epithelioid. Recently malignant epithelioid variant of angiomyolipoma has been further described. We would like to compare these two histologic types receiving surgical treatment of our own experience
We collected 53 cases of renal angiomyolipoma from our hospital receiving surgical intervention from September 2010 to August 2014.
Among these cases, 38 (71.7%) was female with medium age 56.9 year-old. 15 male (28.3%) with medium age 58.7 year-old. 21 of 53(39.6%) had right side AML with left 30 of 53(56.6%) and bilateral 1 of 53(1.9%). 3 of 53 (5.7%) received neprectomy and 50/53(94.3%) received partial nephrectomy. Classic angiomyolipoma accouted for 92.5%(49/53) of all cases with epithelioid variant 7.5%(4/53). No recurrence was noticed among classic type with average follow-up length 32.6 months. Recurrence was noted in one of epithelioid variant in 31 months follow-up.
Renal angiomyolipoma is a benign neoplasm consisting of thick-walled aneurysmal vessels, smooth muscle, and varying levels of mature adipose tissue. Recently malignant epithelioid variant of angiomyolipoma has been further described since it was presented on 1997 by Eble and colleagues. Here, We compared these two histologic types receiving surgical treatment of our own experience and we would like to compared it with data of other institute to see of there’s any differences and the cause leading to it.