奇美醫學中心 外科部 泌尿外科，1泌尿腫瘤科
Retroperitoneal liposarcoma: experience of chi-mei hospital
Hsuan-Ying Ho, Kuan-Hua Huang1
Division of Urology, Department of Surgery, 1Division of Uro-Oncology
Chi Mei Medical Center
Purpose: Retroperitoneal liposarcomas are rare malignant tumor with an aggressive disease course and high recurrent rate. In this article, we will share our experience in treating retroperitoneal liposarcoma and describe the tumor behavior we observed.
Materials and Methods: During January 2010 to December 2014, 11 patient are treated in our hospuital for retroperitoneal liposarcomas. We review the treatments (surgical or non-surgical), clinical presentation, tumor behavior, pathological subtype, and the characteristics of recurrent tumor.
Results: There are 11 patients of retroperitoneal liposarcoma enrolled in this analysis. 9 patients are female, and 2 are male. 7 patients are well-differentiated liposarcoma, and 4 are de-differentiated liposarcoma. One patient died one month after surgical excision of tumor because of pneumonia. One patient has no recurrence in 3 years of follow-up. One has bone metastasis at the time of diagnosis. 8 patients are found recurrent and receive repeated surgical excision of tumor, and 3 of them experience second recurrence. One patient experience third recurrence, and one has forth recurrence. The mean time to recurrence is 40 months. 4 patients have surgical margin involved with tumor, and the mean recurrence time in this subgroup is 5 months.
During the past 4 years, 11 patients with retroperitoneal liposarcoma receiving surgical excision of tumor have been followed at our hospital. There is no obvious difference in tumor recurrence between pathology subtypes. Patients with positive surgical margin experience shorter time to recurrence.