應用正子電腦斷層攝影於診斷原發性上泌尿上皮癌
歐建慧、 蔡育賢、楊文宏、林永明
國立成功大學醫學院附設醫院泌尿部
Detecting primary upper tract urothelial cancer with by whole body FDG PET/CT
Chien-Hui Ou, Wen-Horng Yang, Yung-Ming Lin
Department of Urology, Medical College and Hospital, National Cheng-Kung
University, Tainan, Taiwan
Abstract
Purpose: The study aimed to evaluate the possibility of applying 18F-fluorodeoxyglucose positron-emission tomography (FDG PET/CT) for detecting upper tract cancer.
Material and Methods: 37 patients who had undergone preoperative
FDG PET/CT for their suspected upper tract urothelial cancer from January 2010 to December 2015, were retrospectively enrolled for comparison with the postoperative histological findings of nephroureterectomy.
Results. The histological findings revealed 39 urothelial malignancies in 37 nephroureterectomy specimens. The sensitivity of FDG PET CT was 87.1% (34/39) in detecting the primary upper tract urothelial cancer. 2 patients without FDG PET/CT avid tumor were diagnosed with Ta, low grade urothelial cancer. In two patients with two separated upper tract tumors by histology of nephroureterectomy, only one avid tumor was found in FDG PET/CT. In one patient with annular type T3 ureteral cancer, no definite evidence of FDG-avid tumor was found in the ureter.
Conclusions. FDG PET/CT may serve as a feasible supplementary method for the
diagnosis of upper tract urothelial malignancies but may miss low grade, low stage, small size or annular type of urothelial cancer.