評估正子電腦斷層造影對於上泌尿道泌尿上皮癌之診斷及分期效果
黃冠勳、歐建慧、楊文宏
國立成功大學醫學院附設醫院泌尿部
Evaluation of Fluorodeoxyglucose positron emission tomography/computed tomography for diagnosis and staging of upper urinary tract urothelial carcinoma
Kuan-Hsun Huang, Chien-Hui Ou, Wen-Horng Yang
Department of Urology, Medical College and Hospital, National Cheng-Kung University, Tainan, Taiwan
Purpose: To evaluate the ability of Fluorodeoxyglucose positron emission tomography /computed tomography(18F-FDG PET-CT) in primary diagnosis and detection of upper urinary tract urothelial carcinoma by comparing with final pathological result.
Materials and Methods: We retrospectively evaluated clinicopathological records of patients in our institute. All patients suspicious to have upper urinary tracts malignancies were received 18F-FDG PET-CT, which was followed by pathological-proved procedures such as ureteroscopic biopsy, CT-guide biopsy, Nephroureterectomy or Hand-assisted Retroperitoneoscopic Nephroureterectomy (HARN). 21 patients were included in this study. There were 12 women and 9 men with a median age of 76 years old (range 34~89y/o).
Results: Of 21 patients in study group, 12 patients received HARN, 3 had URS biopsy, 1 CT-guide biopsy and 5 open Nephroureterectomy. There were 5, 3,5, 7 patients with pTa, pT1, pT2, pT3 respectively. 3 patients were diagnosed with lymph nodes metastasis by PET-CT, and 2 patients with tissue proved lymph node metastasis. 20 showed definite FDG uptake in initial or delay phase. Positive predictive rate was 95 %.
Conclusion: These preliminary results of this study with small number of patients showed that FDG-PET/CT is another effective diagnosis in detection of UTUC.