小於55歲男性攝護腺切片的臨床特徵
黃柏仁1、邱逸淳1,2,3
1臺北市立聯合醫院忠孝院區 外科部 泌尿外科；2臺北市立聯合醫院仁愛院區 外科部 泌尿外科；3國立陽明大學 醫學院泌尿學科
Characteristics of men younger than 55 year-old receiving transrectal ultrasound prostate needle biopsy (TRUS biopsy)—the experience of the community hospital
Po-Jen Huang1, Yi-Chun Chiu1,2,3
1Division of Urology, Department of Surgery, Taipei City Hospital, Zhong-xiao Branch
2Division of Urology, Department of Surgery, Taipei City Hospital, Ren-Ai branch
3Department of Urology, School of Medicine, National Yang-Ming University, Taipei, Taiwan
Purpose: Early detection of prostate guideline from American Urological Association (AUA) in 2013 does not recommend routine prostatic specific antigen (PSA) screening in men younger than 55 year-old at average risk. The purpose of this study is to investigate the characteristics of TRUS biopsy for patients younger than age of 55, in a hope to assess the benefit of TRUS biopsy and the occurrence of prostate cancer in this population.
Materials and Methods: Based on retrospective medical records, 812 male patients who received TRUS biopsy during December 2007 to December 2014 at Zhongxiao Branch of Taipei City Hospital were included. Of them, 57 men (7%) were younger than fifty five year-old. We compare the age, pre-biopsy, PSA, prostate size, and adenoma size between prostate cancer group and benign prostatic hyperplasia group.
Results: In these 57 men, 6 of them (10.5%) had prostate cancer (group A), and 51 men had benign prostatic hyperplasia (group B). The average age of the group A and B was 51.0 ± 3.7 and 50.8 ± 3.1 year-old (P=0.23). The mean PSA of group A and B was 15.3 ± 12.3 and 7.2 ± 4.5 ng/ml (P<0.05). The mean prostate size of group A and B was 23.3 ± 6.1 and 33.6 ± 14.8 ml (P=0.04). The mean adenoma size of group A and B was 8.7 ± 3.0 and 10.3 ± 5.5 ml (P=0.12).
Conclusions: Among selected male patients younger than age of 55, TRUS biopsy was with a positive detection rate of 10%, and prostate cancer may be detected in patients with higher level PSA and smaller prostate size.