泌尿道結石患者有較高的焦慮症風險
連啟舜1,黃志平1,鍾季容2,3,林橙莉4,5,張兆祥1,5
中國醫藥大學附設醫院泌尿部1
中國醫藥大學公共衛生學院風險管理系2
中國醫藥大學醫研部3
中國醫藥大學附設醫院健康資料管理辦公室4
中國醫藥大學醫學系5
Increased risk of anxiety among patients with urolithiasis: A
nationwide population-based cohort study
Chi-Shun Lien1, Chi-Ping Huang1,Chi-Jung Chung2,3, Cheng-Li Lin4,5 and Chao-Hsiang Chang1,5
Department of Urology, China Medical University Hospital1
Department of Health Risk Management, College of Public Health, China Medical University2 Department of Medical Research, China Medical University Hospital3
Management Office for Health Data, China Medical University Hospital4
College of Medicine, China Medical University, Taichung, Taiwan5
Purpose:
To investigate whether patients with urolithiasis are at an increased risk of
anxiety and depression.
Materials and Methods:
We used universal insurance claims data in Taiwan from 2000 to 2011 to
identify patients with newly diagnosed urolithiasis (n = 32 617) and those without
urolithiasis (n = 130 465). Incidences, hazard ratios, and incidence rate ratios of anxiety
and depression were determined in both cohorts in terms of baseline demographic
characteristics and comorbidities until December 2011.
Results:
The urolithiasis cohort yielded a higher incidence of anxiety (11.9 vs 6.91 per
1000 person-years) with an adjusted hazard ratio of 1.5 (95% confidence interval 1.42–
1.57) than the non-urolithiasis cohort. The urolithiasis cohort also showed a higher
incidence of depression (5.79 vs 3.95 per 1000 person-years) with an adjusted hazard
ratio of 1.26 (95% confidence interval 1.18–1.35) than the non-urolithiasis cohort.
Regardless of the patients’ baseline comorbidities, patients with urolithiasis showed a
higher incidence rate ratio of anxiety and depression than those without urolithiasis
(with no comorbidities: adjusted hazard ratio 1.62, 95% confidence interval 1.49–1.76] for
anxiety and adjusted hazard ratio 1.37, 95% confidence interval 1.23–1.54 for
depression).
Conclusion:
Urolithiasis is recurrent, and significantly associated with anxiety and
depression. Therefore, urologists should diagnose patients suspected with this disease
and provide proper medical care.