兒童攝護腺橫紋肌肉瘤–個案報告與文獻回顧
郭名捷 蘇家震 沈坤宏
奇美醫學中心 外科部 泌尿外科
Experience in Pediatric Rhabdomyosarcoma in Prostate
Case Report and Literature Review
Ming-Chieh Kuo, Chia-Cheng Su, Kun-Hung Shen
Division of Urology, Department of Surgery
Chi-Mei medical center, Tainan, Taiwan
Abstract
Introduction
Rhabdomyosarcoma is a children-predominant soft tissue malignant tumor of mesenchymal origin. The overall incidence is 4.5 per 1 million children as previous literature reported. The tumor was mainly found in head and neck field and extremities. Since the incidence was low, there was no well-established treatment suggestion or guidelines.
Material and Methods
Here we present a 16-year-old boy who suffered from acute urine retention, and was further diagnosed with prostate embryonal rhabdomyosarcoma. With consensus made by urologist, medical oncologist, and redio-oncologist, further treatment with concurrent chemoradiotherapy was arranged. Nearly complete response without residual tumor was noted then. We also reviewed and compared the previous literature with our current experience.
Conclusion
Pediatric rhabdomyosarcoma is a rare disease. Due to the majority of patients was children and adolescent, aggressive CCRT along could be well-tolerated and possible with excellent response. Surgical intervention was remained for selected patient for further local control.