引發勃起功能障礙風險與阻塞型睡眠呼吸中止症的全國調查
盧致誠 范文宙
奇美醫療財團法人柳營奇美醫院 外科部 泌尿外科
Increased risk of erectile dysfunction in patients with
Obstructive sleep apnea: a nationwide study
Chih-Cheng Lu, Wen-Chou Fan
Division of Urology, Department of Surgery, Chi Mei Medical Center, Liouying, Tainan
Purpose:
Obstructive sleep apnea (OSA) syndrome is a disease with recurring episodes of apnea or hypopnea from total or partial pharyngeal collapse during sleep. This study investigates the possible association between OSA and erectile dysfunction(ED).
Materials and Methods:
A retrospective cohort study was conducted with 2 study groups: an OSA group and a matched non-OSA control group. The nationwide database from the National Health Insurance (NHID) was used. OSA was defined in a male patient if he had at least two outpatient service claims with the codes of OSA (ICD-9-CM code 780.51, 780.53, 780.57, 327.23) at any hospital or local medical clinic and received a polysomnography test or had a single hospitalization for OSA among the 4 claims diagnosis codes. In Taiwan, ED is diagnosed based on the results of a self-administered International Index of Erectile Dysfunction-5 questionnaire. ED (ICD-9 coded as 607.84) was identified only through a diagnosis made during admission or by a specialist during 3 hospital visits. Any diagnosed ED before OSA was excluded. All individuals in the NHID were encrypted for confidentiality.
Results:
A total of 3831 OSA patients and 15324 age, gender, and index date matched non-OSA patients were followed at least 10 years. Approximately 65% of the group was younger than 50 years old, 24% was 50 to 65 years old, and 11% was older than 65 years old. Patients with OSA had a higher prevalence of ED.
Conclusion:
The possible association between OSA and ED is shown from this nationwide study. Awareness of OSA and risk of developing ED is suggested for the physicians. .