在骨盆腔癌症深層局部溫熱治療對膀胱功能的影響-早期結果報告
呂其峰1、 李良明1,2、林克勳1,2、林雍偉1,2、蕭志豪1,2、溫玉清1,2*
1台北市立萬芳醫院（委託臺北醫學大學經營辦理）泌尿科
2臺北醫學大學醫學系泌尿學科
Evaluation of the urinary bladder function among the patients with pelvic cancer undergoing regional hyperthermia treatment - preliminary data report
Chi-Fong Lu1, Liang-Ming Lee1,2, Ke-Hsun Lin1,2, Yung-Wei Lin1,2, Chi-Hao Hsiao1,3, Yu-Ching Wen1,2*
1 Department of Urology, Wan Fang Hospital, Taipei Medical University
2Department of Urology, School of Medicine, College of Medicine, Taipei Medical University
Purpose:
Currently, the effect of pelvic regional hyperthermia treatment to the urinary bladder function is still unknown. We plan to evaluate the urinary bladder function among the patients with pelvic cancer undergoing regional hyperthermia treatment.
Materials and Methods:
We enrolled patients receiving hyperthermia treatment due to bladder cancer, rectal cancer and other pelvic cancers in our hospital. Exclusion criteria include patients with hyperthermia treating areas outside the pelvis, urinary tract infection, double J placement or altered medications toward lower urinary tracts symptoms. International prostate symptoms score (IPSS) questionnaire and urine flow rate (UFR) were recorded from the patients before receiving pelvic hyperthermia treatment, and 1 month later after pelvic hyperthermia treatment. Paired-t test was used to analyze the differences of IPSS and UFR before and after pelvic hyperthermia treatment. Subgroup of each domains and scores were also analyzed.
Result:
From March 2016 to March 2018, 40 patients underwent hyperthermia treatment were included in our study. After excluding patients, 13 patients’ data were enrolled in our study. The mean total IPSS score was decreased from 7.4 to 3.9, (p=0.082). Subgroup analysis revealed no significant differences in each IPSS subscores. However, there is trend toward improving the total IPSS score. UFR revealed no significant differences either (18 to 19 ml/sec, p=0.110).
Conclusions:
In our preliminary data, pelvic hyperthermia treatment may not affect the urinary bladder function. There are trends toward the improvement of the total IPSS score and maximum urine flow rate. However due to our limited data, significant differences is not reached.