Giant verrucous squamous cell carcinoma of external genitalia can be treated through en-bloc resection with resurfacing using the superficial circumflex iliac artery perforator flap: a case report and literature review.
Chih-Jen Wang, Wei-Ting Kuo
Division of Urology, Department of Surgery, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
A 65-year-old man presented with one papillomatous tumor that had been growing gradually for about 20 years over his penile shaft and pubic area. Physical examination found a verrucous and hyperkeratotic protruding tumor with a foul odor. Skin biopsy revealed a giant condyloma acuminatum of Buschke and Lowenstein with moderate dysplasia. The serum SCC antigen level was 7.4 ng/mL. No reaction was noted in the results of HPV, HIV, and syphilis survey. An abdominal CT and gallium scan disclosed no metastasis except for a giant condyloma acuminatum on the skin.
We performed tumor excision with resurfacing using the superficial circumflex iliac artery perforator flap. The final pathology report revealed giant verrucous squamous cell carcinoma.
Such acuminatum is a rare, locally invasive form of tumor that may undergo malignant transformation. Verrucous carcinoma of the external genitalia has been reported to have limited metastatic potential. Wide excision is the treatment of choice.