CONUT營養評估指標對pT1非肌肉侵襲性膀胱腫瘤之盛行率預測
之統合分析及文獻回顧

黃品叡、陳丕哲、沈正煌、林昌德、鄭明進

戴德森醫療財團法人嘉義基督教醫院 外科部 泌尿科

Meta-analysis and Systematic Review of the Prevalence of pT1 Non-muscle Invasive Bladder Cancer via Controlling Nutritional Status (CONUT) Score

Pin-Jui Huang, Pi-Che Chen, Cheng-Huang Shen, Chang-Te Lin, Ming-Chin Cheng

Department of Urology, Ditmanson Medical Foundation Chia-Yi Christian Hospital, Chia-Yi, Taiwan

Introduction:

Non-muscle invasive bladder tumor is a common disease in urology, and the CONUT nutritional assessment index has been pointed out in many studies that it has predictive value for the prevalence of tumors. This article hopes to compare the prevalence of pT1 non-muscle invasive bladder tumors with CONUT nutritional assessment indicators by empirical methods, so as to consider clinical treatment options.

Method:

Answerable clinical questions were formed based on empirical methods, PICO and keywords were set, and MeSH term and Bollinger logic were used to search and retrieve databases such as PubMed, Cochrane library, and Airiti Library. A total of 8 articles were obtained in the preliminary search, and duplicates and inconsistencies were excluded. For the purpose of the research and the literature that did not match the theme of PICO, 2 literatures were finally included, and the literature review was conducted with ROBINS- I , a non-randomized controlled trial evaluation tool .

Result:

A total of 182 people were involved in the above 2 documents, and the meta-analysis software Review Manager (version 5.4) was used for meta-analysis. The results showed that compared with those with lower CONUT nutritional assessment indicators, those with higher CONUT nutritional assessment indicators had higher probability of pT1 non - muscle invasive bladder tumors. The risk ratio (RR) was 4.17 (95% c.i. 2.31 to 7.53, p < 0.01, I² = 17%).

Conclusion:

According to literature review and meta-analysis, those with higher CONUT nutritional assessment index scores have a higher probability of developing pT1 non -muscle invasive bladder tumors than those with lower CONUT nutritional assessment index scores . Based on the above conclusions, it is recommended to predict the prevalence of pT1 non-muscle invasive bladder tumors with the CONUT nutritional assessment index, in order to benefit patients and improve their well-being.