Normal post void residual urine in healthy adults

健康成年人的膀胱餘尿量

Lim Li Yi^1,2、Stephen Shei Dei Yang¹

林利憶^1,2，楊緒棣¹

1. Division of Urology, Department of Surgery, Taipei Tzu Chi Hospital, New Taipei, Taiwan （臺北慈濟醫院泌尿科;
2. Unit Urology，Department of Surgery, Hospital Canselor Tuanku Muhriz (馬來西亞囯大醫院泌尿科)

Purpose: To establish normal reference value of post-void residual (PVR) urine volume in “healthy” adults.

Methods: Adults were recruited to undergo a uroflowmetry and PVR. Those with neurological disorders, malignancy, diabetes, known lower urinary tract dysfunction, urinary tract infection within the previous 3 months, and a moderate to severe IPSS score (≥8), were excluded from the study. Constipation was defined as Rome IV ≥2.

Results: Of the 883 adults enrolled in this study 194 (22.3%) did not complete the questionnaires or perform the uroflowmetry, 284 (30.4%) met ≥1 exclusion criteria and thus were excluded. In addition, 24 and 23 uroflowmetry were excluded due to artifacts and low bladder volume (BV) (<100mL), respectively. Finally, 355 uroflowmetry and PVR data from adults aged 36 to 85 (mean 58.5±9.0) were examined. There was a significant relationship between BV and PVR (p<0.05). When the BV exceeded 528mL and 518mL, the PVR in mL and % BV increased dramatically. There are no gender differences, and PVR was unaffected by functional constipation. A multivariate analysis revealed that BOD had a significant influence on PVR (p<0.01), but age, gender, and Rome IV score did not. After removing the BOD results, the PVR in 90th and 95th percentiles were 52.6ml (20.2% BV) and 69.5ml (25.4% BV), respectively.

Conclusion: It is important to repeat PVR in the setting of BOD. If a person's PVR exceeds the 90th or 95th percentile of normal adults' PVR, additional investigations and treatment may be warranted. Further studies are required to substantiate these recommendations.