愷他命濫用的時間長短與下尿路症狀和低落情慾有關
劉英博、許竣凱、張尚仁、楊緒棣
新店慈濟醫院 外科部 泌尿科; 花蓮慈濟大學
Duration of Ketamine Abuse Was Associated With Lower Urinary Tract Symptoms and Low Mood
Yin-Boh Liu, Chun-Kai Hsu, Shang-Jen Chang and Stephen S. Yang
Division of Urology, Taipei Tzu Chi Hospital, New Taipei, Taiwan and School of Medicine, Buddhist Tzu Chi University, Hualien, Taiwan.
Purpose: This is the first report on the relationship between duration of ketamine abuse and lower urinary tract symptoms and low mood in young adults.
Materials and Methods: After obtaining IRB approval, a structured questionnaire was distributed to young adults who were caught by policemen for using ketamine and were asked to attend educational course in Nov., 2015 and Feb., 2016.
The questionnaire consists of duration and dose of ketamine abuse, International Prostate Symptoms Score (IPSS), short form International Inventory for Erectile Function (IIEF-5), female sexual function index (FSFI) and brief score of mood (BSRS-5). Mild, moderate and severe depression is suspected if BSRS-5 sum score are 6-9, 10-15 and 15-20, respectively.
Results: Of 130 persons 14 (11.8%) refused to fill questionnaire. Mean age of the 116 persons was 27.1±4.4 years. Education level of high school or under was 81%. Mean duration of ketamine abuse in 84 persons was 24.5 months. Duration of abuse was <12 months in 32 (38.1%), 12-24 months in 27 (32.1%) and >24 months in 25 (29.8%). Duration of ketamine abuse was positively related to IPSS score (p=0.05) and BSRS score (p=0.037). Erectile dysfunction was noted in 19 (28.2%) of 60 male abusers. Dose of ketamine abuse was note associated with IPSS or BSRS.
Conclusions: Most ketamine abusers were male with low educational levels. Duration of ketamine abuse was associated with lower urinary tract symptoms and low mood. In addition, erectile dysfunction was frequently observed in ketamine abusers.