鄭人豪、裘坤元

臺中榮民總醫院外科部泌尿外科

Jen-Hao Cheng, Kun-Yuan Chiu.

Divisions of Urology, Department of Surgery, Taichung Veterans General Hospital, Taichung, Taiwan

 

Small cell carcinoma of urinary bladder (SCCB) is very rare and accounting for< 1% of all bladder tumors. Its has highly aggressive behavior and high metastatic potential. We report a patient with SCCB managed by surgery combined chemotherapy and we would provide a brief review of SCCB.

A 55-year-old woman was suffered from gross hematuria since May, 2015 and received transurethral resection of bladder tumor (TURBT) by local medical doctor in Oct.,2015 and pathology report showed small cell carcinoma of urinary bladder without mention of depth of urinary bladder invansion. She came to our hospital to received repeated TURBT and pathology report showed small cell carcinoma combined with high grade urothelial carcinoma with muscular layer (detrusor muscle) invasion. Chest X-ray was normal and the abdominal CT revealed mass lesion about 25mm located over Lt lateral base with focal UB wall thickening. She received neo-adjuvant chemotherapy with Methotrexate(MTX), Etoposide (VP-16) and Cisplatin for three times. Then radical cystohysterectomy with BPLND and ileal conduit reconstruction was performed and pathology report showed residual small cell carcinoma invaded to deep muscularis propria, lymph node invasions: 0/32, pathological TNM stage: ypT2bN0. Patient recovered well and followed up at our hospital.