氣候因子對於高尿酸血症病人結石盛行率之影響
曹書瀚、王敘涵、張哲睿、鄧子麒、朱聖賢、陳孝文、王大民、江仰仁、劉冠麟、林國仁
林口長庚紀念醫院 泌尿科
The impact of climate factors on the prevalence of urolithiasis among patients with or without hyperuricemia
Shu-Han Tsao, Hsu-Han Wang, Che-Jui Chang, Tzu-Chi Teng, Sheng-Hsien Chu,
Hsiao-Wen Chen, Ta-Min Wang, Yang-Jen Chiang, Kuan-Lin Liu, Kuo-Jen Lin
Department of Urology, Chang Gung Memorial Hospital, Taipei, Taiwan


Purpose: Urolithiasis is a common disease with high prevalence and recurrence. There are evidences that meteorological factors affect urinary stone formation. On the other hand, the relation of temperature and humidity to the risk of recurrent gout attacks was also confirmed. However, the association between serum uric acid concentrations and incidence of urolithiasis remains unclear. The aim of this study is to analyze the effects of climate parameters on the numbers of shockwave treatments for urinary stones among patients with or without hyperuricemia in our hospital.

Materials and Methods: We retrospectively reviewed the records of extracorporeal shockwave lithotripsy (ESWL) performed in our hospital from January 2017 to December 2017. Climate data of the corresponding months were collected from Central Weather Bureau. The available monthly meteorological data included highest, lowest, and average temperatures, humidity, rainfall, total rain days, sunshine hours, and average atmospheric pressure. Patients was divided into subgroups according to serum uric acid concentrations. Correlations were used to check the association of each climate factor to monthly ESWL numbers of total, hyperuricemic, and non-hyperuricemic group.

Results: There are 1300 ESWL numbers in our hospital in 2017. The number of hyperuricemic group is 330 and that of non-hyperuricemic group is 970. The monthly ESWL number was positively correlated to temperature (r = 0.642), while it was negatively correlated to atmospheric pressure (r = –0.686). The correlation remains in non-hyperuricemic group. Monthly ESWL number of non-hyperuricemic group was positively correlated to temperature (r = 0.656), while it was negatively correlated to atmospheric pressure (r = –0.653). The correlation becomes insignificant in the hyperuricemic group.

Conclusions: Temperature and atmospheric pressure are associated with monthly ESWL number, while the association is eliminated in hyperuricemic patients.