感染範圍或傷口菌種數可否作為佛尼爾氏壞疽病人住院天數之指標?
張哲綱、林宗彥
國立成功大學醫學院附設醫院 泌尿部
Is extent of infected area or the numbers of bacterial strains from wound culture can be the indicator of duration of admission on patients with Fournier’s gangrene?
Che-Kang Chang, Tsung-Yen Lin
Department of Urology, National Cheng Kung University Hospital, Tainan, Taiwan
Purpose: Fournier’s gangrene (FG) can be a life-threatening disease worldwide if treatment of surgical and antibiotics intervention was not adequately performed. In recent days, up to 45% of mortality rate is reported if patients are infected with FG. However, there is few studies related to early predicting the duration of admission on patients with FG. Therefore, we investigated on the extensive area of patient infected by FG and the number of bacterial strains from wound culture. We then tried to figure out if there is any association between each of them and the duration of admission.
Materials and Methods: From January 2012 to March 2018, we retrospectively reviewed a total 30 patients with FG identified from National Cheng Kung University Hospital and recorded the extensive area of infection and categorized into 3 groups. The higher the grading represented the more extensive the infected area was. We also calculated the number of bacterial strains from wound culture on each patient. Then, we tried to established a regression model between the duration of admission and each of the indicator. The correlation coefficients were also calculated.
Results: There was no obvious association between the extent of FG and the duration of admission since the correlation coefficient of admission days to grading of extent of gangrene revealed -0.1090. There was also no obvious association between the number of bacterial strains from wound culture and the duration of admission; the correlation coefficient of admission days to number of strains revealed -0.1005.
Conclusions: In this single-center and retrospective study, for predicting the possible duration of admission, both the extent of gangrene and the number of bacterial strains may not be well-established indicators.