腎臟發炎性肌纖維瘤: 案例報導及文獻回顧
蔡佳穆、陳盈伸
高雄榮民總醫院 外科部 泌尿外科
Inflammatory myofibroblastic tumor of kidney: case report and literature review
Chia-Mu Tsai, Yin-Shen Chen
Divisions of Urology, Department of Surgery, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
We present a case with huge retroperitoneal tumor, about 20cm and surgical intervention is the first choice. Transarterial embolization was performed following by resection successfully. The pathological report showed Inflammatory myofibroblastic tumor of kidney and no recurrence was found for seven months. Inflammatory myofibroblastic tumor (IMT) is an uncommon, presumably benign tumor, which is composed by myofibroblastic spindle cells. It usually develops in children or young adults, but can affect people of any age with no gender preference.
Approximately 50% of IMT present with an activation of anaplastic lymphoma kinase (ALK), which is the key stone for the further treatment. Crizotinib can targeted the gene and cause tumor shrinkage, or even cure the disease. IMT of kidney has good prognosis, if complete resection is feasible. In VGHKS, 16 cases had been diagnosed, one case is found in kidney, one in urinary bladder and another is diagnosed within retroperitoneum. Three cases showed no recurrent disease.