犀利士(cialis)在機械手臂協助下攝護腺根除併雙側神經保留術後病人勃起功能的恢復效果討論
李毅彥、歐宴泉、童敏哲、許兆畬、殷約翰、翁瑋駿、黃立華、黃鐘銘
童綜合醫院 外科部 泌尿科
Effect of tadalafil once daily on erectile function in patients after robotic assisted radical prostatectomy with bilateral nerve sparing
I-Yen Lee, Yen-Chuan Ou, Min-Che Tung, Chao-Yu Hsu, Jue-Hawn Yin, Wei-Chun Weng, Li-Hua Huang, Zhon-Min Huang
Divisions of Urology, Department of Surgery, Tungs’ Taichung MetroHarbor Hospital, Taichung, Taiwan
Purpose: The erectile function post nerve-sparing radical prostatectomy remains a problem to resolve. We measured the erectile function in patients who using Tadalafil 5 mg once daily for 6 months after receiving nerve-sparing radical prostatectomy.
Materials and Methods: A total of 69 patients less than 70 years of age who had adenocarcinoma of prostate with normal preoperative EF undergoing nerve-sparing Robotic assisted radical prostatectomy were included in our trial. They used Tadalafil 5mg once daily for 6 months after surgery. The “Internal Index of Erectile Function-Erectile Function domain (IIEF-EF)” score was used to measure the erectile function in patients who took tadalafil 5 mg once daily for 6 months after receiving bilateral or unilateral nerve-sparing robotic assisted radical prostatectomy. The baseline of IIEF score before and after prostatectomy was recorded.
Results: After using Tadalafil 5mg once daily for 6 months, 48 patients (69.6%) had higher or equal IIEF score than preoperative evaluation. However, 21 patients (30.4%) had lower IIEF score than preoperative score. Twenty-four (35%) patients had complaint of flank soreness but the symptom mostly alleviating after 5 weeks usage. One patient could not tolerate the side effect of insomnia after 2 months of tadalafil usage and was excluded in this trial.
Conclusions: Phosphodiesterase 5 inhibitor (tadalafil 5 mg) is safe and tolerable in patients who receive bilateral or unilateral nerve-sparing robotic assisted radical prostatectomy. Tadalafil 5 mg once daily was proven to be effective in restoring erectile function and was suggested to use in patients after radical prostatectomy. The effect after cessation of tadalafil 5 mg once daily need to be evaluated in the future.