使用急性腎衰竭之標準捐贈者腎臟移植之長期結果
游智欽1 賀昊中1* 游棟閔2 歐宴泉1 徐國雄2 程千里1 蘇重光1 王賢祥1
陳卷書1 李建儀1 楊晨洸1
臺中榮民總醫院 1外科部泌尿外科 2內科部腎臟科
Long-term outcomes of kidney transplantation from standard criteria donors with acute kidney injury
Chih-Chin Yu, Hao-Chung Ho*, Tung-Min Yu, Yeu-Chuan Ou, Kuo-Hsiung Shu, Chen-Li Cheng, Chung-Kuang Su, Shian-Shiang Wang, Chuan-Shu Chen, Jian-Ri Li, Cheng-Kuang Yang
1Division of Urology, Department of Surgery, and 2 Division of Nephrology, Department of Internal Medicine, Taichung Veterans General Hospital, Taiwan
Purpose:
Abnormal terminal serum creatinine of donors had been reported as the second frequent causes of kidney refusal. More and more studies have shown a comparable outcome of kidney transplantation from deceased donors with acute kidney injury (AKI) in the first year. However, no long-term outcome of these graft kidney is reported.
Materials and Methods:
We retrospectively reviewed 84 consecutive kidney transplants from 57 standard criteria donors. All recipients were classified into two groups according to donor serum creatinine before kidney procurement. The donor and recipient characteristics and graft outcomes were compared.
Results:
Out of 84 kidney transplants, 56 recipients were in Non-AKI group, and 28 recipients were in AKI group. The mean terminal creatinine were 1.09 and 2.62 mg/dL in Non-AKI and AKI groups, respectively. The short-term graft outcomes, including primary non-function rate, delayed graft function rate, and acute rejection rate was compatible. The long-term renal function, graft survival and overall survival over the first 7 years had no statistic difference.
Conclusions:
Our study reveals AKI before procurement had compatible long-term graft outcomes. The results expand donor pools and encourage transplant centers to use these marginal donors.