使用Gentamicin合併quinolone來預防經直腸前列腺切片術後感染的有效性 - 246位病人的回顧性研究
陳柏華、王百孚、林介山、張進寶、江恆杰、嚴孟意
黃勝賢、陳俊吉、黃國軒、石宏仁、張建祥、陳建廷
彰化基督教醫院 外科部 泌尿科
Effectiveness of gentamicin and quinolone on prevention of infection complications after prostate biopsy - a retrospective study of 246 patients
Pao-Hwa Chen, Bai-Fu Wang, Jensen Lin, Chang-Pao Chang, Heng-Chieh Chiang, Meng-Yi Yan, Sheng-Hsien Huang, Chun-Chi Chen, Kuo-Hsuan Huang, Hung-Jen Shih, Jian-Xiang Zhang, Jian-ting Chen
Divisions of Urology, Department of Surgery, Changhua Christian Hospital, Changhua, Taiwan
Purpose:
This study was done to compare infectious complications between patients with and without a set protocol for prostate biopsy.
Material and Method:
Patients whom underwent prostate biopsy at our hospital from 2001 to 2012 were first identified. Two different groups of patients were then selected from two different years. The cut-off year was 2007, which we started to implement a standardized protocol for prostate biopsy. Patient group without set protocol was collected from January 2001 to December 2001. Patient group with set protocol was collected from January 2012 to December 2012.
Result:
A total of 246 patients were selected from 2 years. Ninety-two patients were collected from January to December 2001 (without set protocol). One hundred fifty-four patients were collected from January to December 2012 (with set protocol). In the first group, the infectious complication rate was 10.75% (10 out of 93 While in the second group, the infection rate was 1.3% (2 out of 154). All the minor complications (such as hematuria, hematospermia, dysuria, etc) were self-resolving within 1 month. Most infectious complications were all managed during OPD hours with oral antibiotics. Only 1 patient required hospitalization (from 2001). All the positive culture results did not reveal any resistant strain species.
Conclusion:
The minor complications were similar in both group and were all self-resolving. Infectious complications were more prevalent in the group without set protocol. Adequate peri-op preparation and post-op antibiotics regimens appears to be helpful in prevention of infectious complications.