功能性膀胱容量與間質性膀胱炎患者症狀的嚴重程度相關
劉惠瑛、莊燿吉
高雄長庚紀念醫院 泌尿科
Functional bladder capacity correlates to severity of symptoms in patients with interstitial cystitis/painful bladder syndrome
Hui-Ying Liu、Yao-Chi Chuang
Division of Urology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University, College of Medicine
Purpose:
To investigate the correlation between functional bladder capacity and the pain scale, and clinical symptoms in patients with interstitial cystitis/painful bladder syndrome (IC/PBS).
Materials and Methods:
A retrospective study of 30 patients with symptoms of IC/PBS were included. Functional bladder capacity was detected according to 3-day voiding diary. Bladder hydrodistention were performed under intravenous sedation or general anesthesia. A self-administered questionnaire containing pain and urgency visual analogue scale (VAS), O’Leary-Sant Symptom and Problem Indexes (including Interstitial Cystitis Symptoms Index (ICSI) and Interstitial Cystitis Problem Index (ICPI)) were obtained. The effects of hydrodistension were evaluated by Global Response Assessment (GRA). A two-sample t test was performed to identify the differences of continuous variables between the two groups with functional bladder capacity of > 350ml and ≤ 350ml, and simple logistic regression was applied to assess functional bladder capacity with pain scale, symptom score, age, and bladder capacity in hydrodistention. The p value <0.05 was considered to be statistically significant. Statistical analyses were performed using SPSS 20.0 statistics software (SPSS Inc., Chicago, IL).
Results:
The baseline character has no significant difference between two groups( functional bladder capacity of > 350ml and ≤ 350ml) in age, pain and urgency VAS, ICSI, ICPI, or post-voiding residual urine amount. There is a trend of higher pain scale and symptom score as functional bladder capacity decreased. Furthermore, mean urgency in 3-day voiding diary, bladder capacity on hydrodistention, and GRA showed statistically significant difference between two groups.
Conclusion:
Functional bladder capacity correlates with pain scale and symptom scores. The group of functional bladder capacity > 350ml has larger bladder capacity in hydrodistention and significantly symptoms improvement after hydrodistension.