中藥與失智症排尿困難之相關性研究
柳瑞明1,2, 林柏宏3, 林舜穀4, 莊恆彰1, 許仁駿5
1衛生福利部桃園醫院 外科部 泌尿科;2國立陽明大學醫學系; 3林口長庚醫院 泌尿科；4臺北市立聯合醫院 仁愛醫院 中醫部; 5 國防醫學院 生命科學研究所
Traditional chinese medicine therapy reduces dysuria in dementia patients
Jui-Ming Liu1,2, Po-Hung Lin3, Shun-Ku Lin 4, Heng-Chang Chuang1, Ren-Jun Hsu 5
1Division of Urology,Department of Surgery Taoyuan General Hospital, Ministry of Health and Welfare
2Faculty of Medicine, National Yang-Ming University, Taipei, Taiwan
3 Department of Urology, Chang Gung Memorial Hospital
4 Department of Chinese medicine, Taipei City Hospital, Ren-Ai Branch
5 Graduate Institute of Life Sciences, National Defense Medical Center
Background
To test the association between the long-term effects of TCM and the risk of indwelling catheterization in dementia patients with dysuria.
Methods
We used the 1997–2013 National Health Insurance Research Database (NHIRD) of Taiwan. The association between the use of TCM and catheter indwelling in dementia patients with dysuria was examined by multiple logistic regression analysis.
Results
A total of 11,069 patients with dementia were enrolled and 3982 participants who received medication for treat dysuria. There were 2121 in TCM users and 1861 in TCM non-users with a mean follow-up period of 7.25 years. Multivariate regression revealed that use of TCM decreased the risk of indwelling catheterization in dementia patients (adjusted hazards ratio (aHR) = 0.58, 95% confidence interval (95% CI) : 0.52–0.66) compared to TCM non-users.
Conclusion
TCM may have associated with a reduced risk of indwelling catheterization in dementia with dysuria. Further prospective studies are warranted.