久坐的工作形態對於男性荷爾蒙、性功能及下泌尿道功能的影響
蕭惟中1、謝佐宜1,2、陳文榮1,2、王紹全1,2、陳順郎1,2
中山醫學大學附設醫院 1泌尿科 中山醫學大學 2醫學系
Sedentary workload has negative impacts on male erectile and lower urinary tract function
Ｗei-Chung Hsiao1, Tuzo-Yi Hsieh1,2, Wen-Jung Chen1,2, Shao- Chuan Wang1,2, Sung-Lang Chen1,2,
1Department of Urology, Chung Shan Medical University Hospital, Taichung, Taiwan
2School of Medicine, Chung Shan Medical University, Taichung, Taiwan
Purpose: The aim of this study was to investigate the effect of sedentary workload on hypogonadism and the association with erectile and lower urinary tract functions.
Materials and Methods: A total of 81 male first-line office managers of Taichung commercial bank were enrolled in this study. Serum testosterone, free testosterone, estradiol and PSA were checked in the morning. The International prostate symptoms scores (IPSS), 5-items version of the International Index of Erectile Function (IIEF-5) questionnaires and Saint Louis University ADAM (androgen deficiency in aging males) questionnaire were completed and data were obtained by all the enrolled subjective. Eighty one age-matched health check-up subjective were compared as controls.
Results: The age range of enrolled subjective was between 42 and 67 with an average of 48.9 ± 5.94 years. BMI of participants was larger than control group (24.9 ± 3.3 vs 23.8 ± 2.5, P<0.05). Moring Testosterone level was lower in study group (3.09± 0.89 vs 3.59± 0.72 ng/ml). There was no statistically significant difference in total IPSS scores between study and control groups (10.25± 4.79 vs 9.35± 3.72, p=0.186). However subgroup analysis disclosed study group had significantly higher storage domain of IPSS compared with control group (5.95± 2.21 vs 5.27± 1.63, p=0.029). But the difference was not obvious in voiding domain (4.28± 3.32 vs 4.075± 2.9, p=0.667). Those men with sedentary workload also had lower IIEF scores than control group (19.93 ± 4.08 vs 21.2± 2.76, p=0.0141)
Conclusion: Sedentary workload has negative effects on BMI, testosterone levels and erectile functions. Lower urinary tract symptoms, especially storage symptoms, were related to such work style.