低能量體外震波治療有勃起功能障礙的台灣人的臨床經驗
黃一勝、吳子翔、許柏森、仇光宇、蔡德甫
新光吳火獅紀念醫院 外科部 泌尿科 再生醫學中心
Low intensity extracorporeal shockwave therapy for erectile dysfunction: Clinical experience in Taiwanese patients
Thomas I-sheng Hwang, Tzu-Hwiang Wu, Pai-Sen Hsu, Kuang-Yu Chou, Te-Fu Tsai
Division of Urology, Department of Surgery
Shin Kong Wu Ho-Su Memorial Hospital, Taiwan Taipei
Purpose: Low intensity expracorporeal shockwave therapy (LIEST) has been recently reported to increase local metabolism and angiogenesis, thus improve erectile dysfunction. We herein report the outcomes of treated patients in Taiwan.
Materials and Methods: Patients received 2 treatment sessions per week for 3 weeks, and started another course after 2-weeks interval-period. Between December 2015 to November 2016, 46 patients with poor response to PDE5 inhibitor had received LIEST. The data of ED period, comorbidity, PSA, testosterone, lipid profile, erectile hardness score (EHS), international index of erectile function (IIEF), and international prostate symptom score (IPSS) were collected before treatment. EHS, IIEF and IPSS were followed up after treatments. Response to treatment was defined as successful vaginal penetration.
Results: All patients underwent at least 6 treatment sessions, however, only 28 patients completed total 12 treatment sessions. The EHS and IIEF prior to the treatment were 1.36 ± 0.48 and 6.98 ± 4.74, respectively. After 6 and 12 treatment sessions, EHS and IIEF were improved (2.39±0.55, 10.64±5.66 and
2.55±0.63, 12.5±5.58, respectively) with statistical significance (P<0.001). The response rate was 44.4% (8/18) in 6-session and 60.7% (17/28) in 12-session group. Patients received prostatectomy (N=8) also showed improvement in erectile function. In addition to improved erectile function, improved IPSS was noted in 12 patients (42.9%) who completed 12 sessions.
Conclusion: The new treatment modality, LIEST, demonstrated therapeutic effect for Taiwanese ED patients with poor response to PDE5 inhibitors. Additional effect for LUTS has been noticed. Moreover, LIEST also showed effects in patients who received prostatectomy.