膀胱無症狀之副神經節瘤：案例報告及論文文獻回顧
尤仲豪、顏進恆、于承平、李俊德、蘇忠仁、羅華成
三軍總醫院松山分院外科部泌尿科
Asymptomatic paraganglioma of the urinary bladder: A case report and review of the literature
Chung-Hao, Yu、 Chin Heng, Yen、 Cheng Ping Wu、 Chun Te, Li、 Chung Jen, Su、Hua Cheng, Lo
Divisions of Urology, Department of Surgery, Tri-Service General Hospital Songshan Branch office, Taiwan
Abstract
Introduction:
Paraganglioma of the urinary bladder is rare, account for <1% of all bladder tumors, and asymptomatic bladder paraganglioma is even rarer and not easily recognized.
Case report:
The case, a 75 year-old male, who initially had only complaint of hematuria without any discomfort. He stated no past history of systemic disease including hypertension. Cystoscopy was performed, and nodule-like lesion over posterior wall of bladder wall was revealed accidentally. Transurethral biopsy was done and the pathology report showed paraganglioma. The immunohistochemical stains showed CK7, CK20 were negative. We also stained PSA, Pan-CK, Chromogranin-A, S100, Ki-67 for rule out other cancer. Chromogranin-A and S100 showed positive, paraganglioma of urinary bladder was diagnosed.
Conclusion:
Asymptomatic urinary bladder paraganglioma is rare and not easily diagnosed. Transurethral resection/biopsy for bladder mass is necessary. A pathologic diagnosis rely on immunohistochemical stains.