盧誌明

佛教慈濟醫療財團法人大林慈濟醫院 泌尿科

Chih-Ming Lu

Department of Urology, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi, Taiwan

 

Background: Patients with systemic lupus erythematosus may involve in renal disorders, such as persistent proteinuria or cellular cast in urine, and followed by lupus nephritis. An association between systemic lupus erythematosus and the development of renal cell carcinoma has been reported in a case report. Systemic lupus erythematosus is described as a paraneoplastic syndrome associated with renal cell carcinoma. Actually the nature of the relationship between those two diseases remains unclear.
Case presentation: We report that a 29-year-old female presented to the emergency department with acute abdominal pain and vomiting sudden onset. Spontaneous rupture of the left kidney with massive hematoma over left retroperitoneum was depicted in a computed tomography scan . She had a history of systemic lupus erythematosus for 16 years (diagnosed in the age of 13), followed by the development of lupus nephritis in the age of 17. Simultaneously she initialized hemodialysis due to end-stage renal disease. Besides, she received surgical intervention for Mallory-Weiss tear several years ago. We try to clarify the association between renal cell carcinoma and systemic lupus erythematosus.

Conclusion: The incidence of renal cell carcinoma among patients with systemic lupus erythematosus is rare. The survey of occult renal cell carcinoma may be helpful for those patients involve in end-stage renal disease, rather than systemic lupus erythematosus.