下唇黏膜用於尿道及輸尿管重建--供皮處的後遺症報告

陳柏諺

高雄長庚紀念醫院 泌尿科

Donor Site Sequelae after Lower Lip Mucosa Harvest for Urethral and Ureteral Reconstruction

Po Yen Chen

 Department of Urology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan

Purpose: Oral mucosa graft has become an important graft source in reconstructive urology because of its durability, elasticity, and favorable graft characteristics. Although buccal mucosa is most used, lower lip mucosa may provide an alternative donor site for selected patients undergoing urethral or ureteral reconstruction. However, donor site morbidity after lower lip mucosa harvest remains a concern. We aimed to evaluate the sequelae of lower lip donor sites in patients undergoing urologic reconstruction.

Materials and Methods: We retrospectively reviewed patients since 2024 March to 2026 February who underwent lower lip mucosa harvest for urologic reconstruction at our institution. Patients receiving lower lip mucosa graft for urethral or ureteral reconstruction were included. Donor site outcomes were analyzed according to the number of lower lip harvest sites. Postoperative sequelae including scar formation, numbness, and impairment of mouth opening were recorded. A total of 37 lower lip donor sites from 31 patients were included in the analysis.

Results: Among the 37 lower lip donor sites, 5 sites (13.5%) developed scar formation, 2 sites (5.4%) were associated with persistent numbness, and 1 site (2.7%) resulted in impaired mouth opening. No major donor site complication was identified. Overall, lower lip mucosa harvest was well tolerated, and most donor site morbidities were minor and manageable.

Conclusion: Lower lip mucosa harvest for urethral and ureteral reconstruction is feasible and safe. Although minor donor site sequelae may occur, including scar formation, numbness, and limited mouth opening, the overall morbidity is low and acceptable. Lower lip mucosa represents a useful alternative graft source in selected cases of urologic reconstruction.