使用去細胞異體真皮片進行陰莖增粗術之臨床成效與併發症分析：
短期臨床成效比較

朱信誠

民權精睿泌尿科診所

Clinical Outcomes and Complications of Penile Augmentation Using Acellular Dermal Matrix: A Preliminary Clinical Study

Chu Hsin Cheng

Jingrui urology clinic, Taipei, Taiwan

Purpose: Penile girth enhancement has gained increasing attention in aesthetic urology. Acellular dermal matrix (ADM) is widely utilized due to its excellent biocompatibility, structural stability, and low immunogenicity. This study aims to evaluate the clinical efficacy, patient satisfaction, and complication rates of ADM for penile augmentation.

Materials and Methods: We retrospectively reviewed 13 patients who underwent penile girth enhancement using ADM (MegaDerm; L&C Bio, South Korea) at a single center. The surgical technique primarily involved sub-dartos placement of the matrix. Primary outcomes included the increase in penile length, penile circumference, and glans circumference. Measurements were taken preoperatively and at a minimum follow-up of 1 month. Postoperative complications were also recorded.

Results: The analysis showed significant improvements across all measured parameters. The mean penile length increased from 2.8 ± 1.0 cm. The mean penile circumference increased from 2.2 ± 0.7 cm. Postoperative complications were recorded as follows: transient edema , minor hematoma, and infection, all of which resolved with conservative treatment. Rare occurrences of focal foreskin necrosis were managed with debridement. Regarding aesthetic outcomes, significant indentation or contour irregularities were observed in two patients. Finally, most patients with various complications recovered successfully, however two patients underwent ADM removal surgery.

Conclusions: Penile augmentation with ADM provides a significant and stable increase in both length and girth with high patient satisfaction. However, to optimize outcomes and minimize risks, meticulous postoperative care and the precise evaluation and selection of ADM graft size are of paramount importance. While ADM remains a safe and effective surgical option, the prevention and management of complications—such as foreskin necrosis and contour irregularities—require further standardization and more extensive statistical analysis to refine clinical protocols.