過去十年台灣腎臟癌的發生率與期別分析－高醫體系回朔性分析

張顥瀚¹³, 吳文正¹²³, 李經家¹²³

高雄醫學大學附設中和醫院 泌尿部¹、高雄醫學大學醫學系 泌尿學科²、高雄醫學大學 臨床醫學研究所^３

Tumor characteristics and survival outcomes of renal cell carcinoma during the past decade in Taiwanese population: A dual-center retrospective study

Hao-Han Chang¹³, Shen-Chen Wen¹³, Ching-Chia Li¹²³

1Department of Urology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan

2Department of Urology, School of Medicine, College of Medicine, KaohsiungMedical University, Kaohsiung,

3Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung MedicalUniversity, Kaohsiung, Taiwan

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Purpose:

To assess the native south Taiwan renal cell carcinoma (RCC) profile in the past decade.

Methods:

During 2010–2019, 306 patients newly diagnosed with RCC in Kaohsiung Medical University Hospital and Kaohsiung Municipal Ta-Tung Hospital were included. We compared the data of our cohort with the data of the United States using chi-square test of homogeneity. Cox regression models were used to evaluate variables related to patients’ and cancer characteristics. The Kaplan-Meier survival model was used to observe the prognostic role of cancer staging and histology subtype.

Results:

In our cohort, the proportion of each clinical stage was similar to that mentioned in the United States data, while patients in the current study had younger age at diagnosis. Cancer staging was a prognostic factor in both univariate and multivariate analyses. Histology subtype was an independent prognostic factor. Metastatic tumor and other histology subtypes had the worst survival outcome compared to other variables.

Conclusions:

The baseline characteristics of RCC were determined in our study. In Taiwanese population, tumor staging and histology subtypes of RCC are important prognostic variables.