原發性腎盂淋巴上皮癌
陳浩瑋1,2、闕光瞬1、吳文正1、李經家1、葉信志1、李香瑩1、蔡嘉駿1、黃俊農2
1高雄市立大同醫院 泌尿科；2高雄醫學大學附設中和紀念醫院 泌尿部
Primary lymphoepithelioma-like carcinoma of the renal pelvis
Hao-Wei Chen1,2, Kuang-Shun Chueh1, Wen-Jeng Wu1, Ching-Chia Li1, Hsin-Chih Yeh1, Hsiang-Ying Lee1, Chia-Chun Tsai1, Chun-Nung Huang2
Divisions of Urology, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung, Taiwan1;
Department of Urology, Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Taiwan2
Lymphoepithelioma-like carcinoma (LELC) is best known to occur in the nasopharynx. When LELC occurs in the urinary tract, this extremely rare neoplasm most commonly affects the bladder but has also been reported in the renal pelvis, ureter, prostate, and urethra.
We present a case of LELC arising in the right renal pelvis of a 73-year-old woman with hematuria and hydronephrosis. Computed tomography demonstrated right renal pelvis tumor. Ureteroscopy biopsy showed papillary urothelial neoplasm of low malignant potential. An operation with hand-assisted laparoscopic right nephroureterectomy and extravesical bladder cuff exision was carried out. The pathologic examination showed pure type of LELC, pT2N0.
Unlike lymphoepithelioma in the nasopharynx, immunohistochemical analysis of this urinary LELC was negative for the Epsteine-Barr virus. No disease recurrence was noted at 1-year follow-up. Only ten previous cases of LELC involving the renal pelvis have been reported. This is the first report of a renal pelvis LELC case in Taiwan.